Lectures on Biomedical and Health sciences

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speachIncluded below is a selection of lectures immediately available in The Biomedical & Life Sciences Collection. The library is updated and expanded monthly and contains over 2,100 specially prepared, seminar-style, animated talks by many of the world’s leading experts, including Nobel, Breakthrough and Lasker Prize winners.

Researchers will find many talks relate to subjects relevant to their research – please see below some examples. Extracts, as well as the complete talks, can easily be integrated and embedded in courses to further enrich the teaching and learning experience.

 Neuroscience

  • Protein degradation and defense against neurodegenerative disease 1 By Prof. Alfred Goldberg – Harvard Medical School, USA
  • AMPA-receptors and fast synaptic transmission in the brain By Prof. Stuart Cull-Candy – University College London, UK
  • The clinical features of amyotrophic lateral sclerosis: diagnosis, natural history and epidemiology – Prof. Kevin Talbot, University of Oxford, UK
  • Behavioral phenotyping of mouse models of neuropsychiatric and neurodevelopmental disorders By Prof. Jacqueline N. Crawley – University of California, USA
  • Life course of the brain during normal aging and Alzheimer’s disease – Prof. Caleb Finch, The University of Southern California, USA

Immunology

  • Immunosuppressive mechanisms in myeloid cells – Prof. Dmitry Gabrilovich, University of Pennsylvania, USA
  • Evolution, human-microbe interactions and the “epidemic” of inflammation-related disorders (alias: the hygiene hypothesis) By Prof. Graham Rook – University College London, UK
  • Vector mediated immunoprophylaxis – Dr. Bruce Schnepp, The Children’s Hospital of Philadelphia, USA
  • Airway macrophages in health and disease By Prof. Tracy Hussell – University of Manchester, UK
  • Future directions for vaccine discovery 1 By Dr. Chris Wilson – Bill and Melinda Gates Foundation, USA

Microbiology

  • National and international surveillance of antibiotic resistance 1 by Prof. David Livermore – Public Health England’s Antibiotic Resistance Monitoring and Reference Laboratory, UK
  • Malaria – changing paradigms By Dr. Janet Cox-Singh – University of St Andrews, UK
  • Teixobactin kills pathogens without detectable resistance – Prof. Kim Lewis, Northeastern University, USA
  • Probiotics – Dr. Gregor Reid, Lawson Health Research Institute, Ontario, Canada
  • The challenge of developing drugs for neglected parasitic diseases By Prof. James Mckerrow – University of California San Francisco, USA

Biochemistry

  • Intrinsically unstructured proteins: regulation and disease By Dr. M. Madan Babu – University of Cambridge, UK
  • Enzymology in drug discovery 1 By Prof. Robert Copeland – Epizyme, USA
  • Advances in fibrinolysis – Dr. Paul Kim, McMaster University and Thrombosis and Atherosclerosis Research Institute, Canada
  • Folding and Design of Helical Repeat Proteins By Prof. Lynne Regan – Yale University, USA
  • Cytochrome P450 1 Family: the roles of 1A1, 1A2 and 1B1 in drug metabolism By Prof. F. Peter Guengerich – Dept. of Biochemistry, Center in Molecular Toxicology, Vanderbilt University, USA

Genetics & Epigenetics

  • The molecular mechanism of X chromosome inactivation – Prof. Neil Brockdorff, University of Oxford, UK
  • Structure, evolution and dynamics of gene regulatory networks By Dr. M. Madan Babu – University of Cambridge, UK
  • Heterochromatin, epigenetics and gene expression By Prof. Joel C. Eissenberg – Saint Louis University, USA
  • Epigenetics as a paradigm for cancer treatment: chemically targeting the histone lysine methyltransferase EZH2 By Dr. Sharad K. Verma – GlaxoSmithKline, USA
  • An introduction to genetic association analysis – Prof. Jenny Barrett, University of Leeds, UK

Omics & Systems Biology

  • Systems biology of the cell cycle – Prof. Bela Novak, University of Oxford, UK
  • Interactome networks and human disease – Prof. Marc Vidal, Harvard Medical School, USA
  • Control feedback and cellular responses – Prof. Francis J. Doyle III, UCSB, USA
  • Impact of systems biology on metabolic engineering – Prof. Jens Nielsen, Chalmers University of Technology, Sweden
  • Proteomic technologies and targets: an overview by Dr. Walter Kolch – University College Dublin, Ireland

Cell Biology

  • Traffic problems: inherited disease and intracellular trafficking defect – Dr. Paul Gissen, University College London, UK
  • The ERK1/2 MAPK cascade by Prof. Melanie H. Cobb – University of Texas Southwestern Medical Center at Dallas, USA
  • The Myc transcription factor network by Prof. Robert N. Eisenman – Fred Hutchinson Cancer Research Center, USA
  • O-GlcNAc, an essential regulator of numerous cellular pathways By Dr. Natasha Zachara – Johns Hopkins University School of Medicine, USA
  • Yeast studies on ageing – Prof. S. Michal Jazwinski ,Tulane University School of Medicine, USA

Cancer

  • Genetics of tumor metastasis 1 By Prof. Robert Weinberg – Whitehead Institute for Biomedical Research, USA
  • Chromosome translocations and cancer – Prof. Felix Mitelman, Lund University, Sweden
  • Immune checkpoint blockade in renal cell carcinoma – Dr. David McDermott, Harvard Medical School, USA
  • Functional cancer genomics by Prof. Roderick Beijersbergen – Netherlands Cancer Institute, The Netherlands
  • Pharmacogenomics in cancer therapy – Prof. Sharon Marsh, University of Alberta, Canada

Pharmaceutical Sciences

  • Rules and filters and their impact on success in chemical biology and drug discovery By Dr. Christopher Lipinski – Melior Discovery Inc., USA
  • Structure-based drug design By Dr. Nathan Brown – Institute of Cancer Research, UK
  • Hit to lead by Dr. Michael Rafferty – University of Kansas, USA
  • Quantitative analysis of receptor allosterism and its implication for drug discovery – Dr. Rumin Zhang,  Merck, USA
  • Fragment-based lead discovery by Dr. Daniel A. Erlanson – Carmot Therapeutics, Inc., USA

Clinical Medicine

  • Post-resuscitation syndrome after cardiac arrest – Protecting the Brain – Prof. David Seder – Tufts University School of Medicine, USA
  • Assessment of renal function by Dr. Jochen Raimann – Renal Research Institute, USA
  • Coagulation in sepsis – Prof. Marcel Levi – University of Amsterdam, Netherlands
  • Oral cancer for the general dentist – Dr. Alessandro Villa – Harvard University, USA
  • Identifying the trauma footprint of acquired brain injury by Dr. Christine Durham – RMIT University, Melbourne, Australia

Diseases, Disorders, & Treatments

  • NASH: Update on diagnostics and therapy – Dr. Arun J. Sanyal – Virginia Commonwealth University, School of Medicine, USA
  • CLL: novel prognostics, and updates on therapy 1 – Prof. Jennifer R. Brown – Harvard Medical School, USA
  • Chemotherapy-induced neuropathy: incidence, natural history, measurement, prevention, and treatment – Dr. Charles Loprinzi – Mayo Clinic, USA
  • Inflammatory bowel disease By Prof. Ole Haagen Nielsen – University of Copenhagen, Denmark
  • Psoriasis by Prof. Chris Griffiths – University of Manchester, UK

Metabolism & Nutrition

  • Obesity management: lifestyle and bariatric surgery – Prof. John Wilding, University of Liverpool, UK
  • Dysregulated eating behaviour, eating disorders and obesity by Prof. Ulrike Schmidt – King’s College London
  • Metabolic communication in development and control of obesity 1 by Prof. Elaine Holmes – Imperial College London, UK
  • What did humans evolve to eat? evolutionary perspectives on human nutritional health By Prof. William R. Leonard – Northwestern University, USA
  • The metabolic syndrome by Prof. Jean Pierre Després – University of Laval, Canada

Reproduction & Development

  • Hox gene regulation in vertebrate hindbrain development – Prof. Robb Krumlauf, Stowers Institute for Medical Research, USA
  • Left-Right Asymmetry in Embryonic Development: How epigenetic, biophysical forces and gene activity interplay to determine a major embryonic axis by Prof. Michael Levin – Biology Department, TCRDB, Tufts University, USA
  • Barrier mechanisms in the developing brain: protection or vulnerability? by Prof. Norman Saunders – University of Melbourne, Australia
  • Application of proteomics in fetal and neonatal medicine by Dr. Joost P. Schanstra – INSERM, Toulouse, France
  • Pre-gestational diabetes and pregnancy by Prof. Jeremy J. N. Oats – University of Melbourne, Australia

Agriculture & Environmental Sciences

  • Agricultural genetics for food security – Prof. Robert Henry, University of Queensland, Australia
  • Epigenetics in agriculture – Prof. Graham King, Southern Cross University, Australia
  • Animal behavioural genetics – Prof. Temple Grandin, Colorado State University, USA
  • Biotic stress tolerance and resistance – Prof. Robert Park, University of Sydney, Australia
  • Plant cell wall: structure and biosynthesis by Prof. Debra Mohnen, Dr. Melani A. Atmodjo – The University of Georgia, USA

Methods

  • Modern production of laboratory animals by Dr. Martin Toft – Adlast, DK
  • Statistical techniques in human population genetics – Dr. Garrett Hellenthal, University College London, UK
  • An introduction to randomization for clinical trials 1 – Prof. William Rosenberger, George Mason University, USA
  • Next generation sequencing in genetic diagnostics – Dr. Alan Pittman, University College London, UK
  • Legal and ethical issues in uses of stored tissue in human subjects research by Ms. Gail Javitt – Johns Hopkins University, USA