Girish Gupta1 , J.P.Singh2 , Salil Tandon3 , Santosh Singh1 , C. Nayak4 ,Hari Singh4 , Ch.Ravindar4 , K.R.J.Nair4 , Praveen Oberai4 .
Background and Objectives: Benign Prostatic Hyperplasia (BPH) is the most common condition in elderly men and its incidence is age related. Although clinical evidence of disease occurs less commonly, symptoms of prostatic obstruction are also age related and if untreated affect quality of life. No data regarding clinical as well as diagnostic parameters assessment in cases of BPH in response to homoeopathic medicines is available. Therefore, an observational study on BPH was conducted with 20 pre-decided medicines for the treatment of BPH.
Methods: A collaborative research study between Central Council for Research in Homoeopathy (CCRH), New Delhi and Homoeopathic Research Foundation, Lucknow was planned. A total of121 patients enrolled, out of which 43 completed the study according protocol. Trial medicines selected on the basis of principles of homoeopathy were prescribed and International Prostate Symptom Score (IPSS), Ultrasonography, Uroflowmetry and Prostate Specific Antigen (PSA) were assessed before and after homoeopathic treatment.
Results: After comparing pre and post treatment results, the difference in mean values IPSS, Prostate weight, PSA and Average flow rates were found statistically significant. Maximum Flow Rate and Post Void Residual Urine (PVRU) were found improving but statistically not significant. Lycopodium(n=15), Pulsatilla(n=11), Sulphur(n=8) and Calcarea carb.(n=3) were found to be most useful among 20 trial medicines.
Conclusion: Results obtained from the study are encouraging with findings that 93.0% patients improved clinically with an evidence of positive changes in diagnostic parameters. However, such study with randomized control trial is needed to further validate the usefulness of the homoeopathic medicines.
Keywords: homeopathy; observational study; benign prostatic hyperplasia; international prostate symptom score; lycopodium; pulsatilla; sulphur
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