Tests of Immunological Function with Interpretation


Baseline investigations include full blood count and white cell differential count , acute phase reactants (CRP), renal and liver function tests, urine dipstick and serum immunoglobulins with protein electrophoresis.

Additional microbiological, virological and radiological tests may be appropriate. At this stage it is often clear which category of immune deficiency is being considered

The important serological reactions are:

  1. Precipitation test
  2. Agglutination test
  3. Compliment fixation test
  4. Neutralization test
  5. Opsonisation
  6. Immunofluorescence
  7. Radio immuno assay (RIA)
  8. Enzyme linked immuno assay (EIA)
  9. Immunoelectroblot

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