A New Approach to Repertorization leveraging Artificial Intelligence: Materiazation or Materiomics

Prof. Dr.Nisanth KM Nambison

Abstract
The paper discusses the limitations of traditional repertorization techniques and proposes a new approach, Materiazation or Materiomics, which leverages AI and advanced computing technologies for more efficient and accurate repertorization.

Introduction
The advent of homeopathic repertories was a pivotal development in the pre-computer era, designed to aid practitioners in navigating the vast Materia Medica through indexing of symptoms. These repertories established due to the burgeoning pool of symptoms of Materia Medica to address the human limitations in recalling and correlating vast symptomatic data of Materia Medica for clinical application. Historically, Samuel Hahnemann himself recognized the necessity of such tools to efficiently pinpoint accurate remedies amidst a growing list of drug provings. However, the utility of these repertories was constrained and came under the critism of the master, by their format—either too concise to be thorough or too detailed to be practical—thus leaving them as mere providers of “vague hints” and not definitive solutions.

With the rise of AI (artificial intelligence) and advanced computing, the landscape of homeopathic practice is poised for transformation. AI Large Language Models (LLMs) and other advanced computing technologies offer a profound leap over traditional methods of repertorization. These models can process extensive texts rapidly, providing precise and semantic search capabilities directly within the texts of Materia Medica without the intermediary step of repertorization, instead of traditional cumbersome and outdated search techniques. This capability significantly reduces the time and complexity involved in selecting the most appropriate homeopathic medicine.

For homeopathic practitioners, the integration of AI tools means an alleviation of the tedious processes traditionally involved in remedy selection. AI can quickly analyze the symptomatology and context provided by patients, directly correlating these with relevant remedy profiles from the Materia Medica. This not only speeds up the consultation process but also enhances the accuracy of prescriptions by handling a broader set of data points simultaneously.

Limitations of Traditional Repertorization

Traditional repertorization, the process of finding a suitable homeopathic remedy based on the symptoms of a patient, has several limitations. The process involves converting symptoms into rubrics (standardized symptom descriptions) and then searching for these rubrics in a repertory, an index of symptoms and corresponding remedies. This process can be time-consuming and may not always yield the most accurate results. Furthermore, the alphabetical arrangement of symptoms in a repertory everything is sacrificed for the alphabetical system, leading to the loss of the whole context..

Materiazation: A New Approach to Repertorization

Materiazation or Materiomics is a new approach to repertorization proposed by Dr. Nambison. This approach involves repertorization directly from Materia Medica, the comprehensive directory of homeopathic remedies, without the need for converting symptoms into rubrics. This approach allows for a more holistic consideration of the patient’s symptoms and avoids the loss of context associated with traditional repertorization.

Application of AI in Homeopathic Science

AI, specifically LLMs and advanced computing, can be effectively used for more than just text retrieval in homeopathic science. LLMs can understand natural language, consider the context of the search to give more relevant results, figure out the intent behind a search query, differentiate between multiple meanings of a word or phrase, handle and answer complex questions effectively, and provide human-like responses. These capabilities make LLMs particularly useful for repertorization.

HomeoXpert: A Specialized AI for retrieving homeopathic knowledge

HomeoXpert, developed by Dr. Nambison and nambison, is a specialized version of ChatGPT that provides information on homeopathy based on specific texts from renowned homeopathic authors. HomeoXpert can provide more accurate and contextually relevant answers, handle queries on topics it was not specifically trained on by leveraging the retrieval mechanism to access up-to-date or specialized information, and scale

Hahnemann’s Contribution to the Development of the Homeopathic Repertory

The concept of the Homeopathic Repertory, derived from the Latin term ‘repertorium’ meaning an inventory. As early as 1805, Hahnemann’s book, ‘Fragmenta De Viribus Medica Mentorum Positivis’, contained an index in its second part. In addition, he published another short repertory, the ‘Aperture Repertory Symptom Dictionary’, in 1817 in Latin. Dr. Richard Hael wrote about Hahnemann’s passion for the repertory, further highlighting his significant contributions to this field.This was a period when Hahnemann began the process of cataloguing all the symptoms collected from an increasing number of provings he was conducting at the time.

Over time, Hahnemann’s alphabetical list of symptoms expanded to four volumes. However, these volumes were never published. It was Hahnemann who first recognized the necessity for an index to recall the symptoms from the ever-growing proving’s data.

Several masters, including Dr. Jahr and Ruckert, attempted to create such an index, but none were able to meet the standards set by Dr. Hahnemann.

The Necessity for a Repertory in Homeopathy

The need for a repertory in homeopathy was driven by several factors. One of the primary reasons was the response to the rapidly expanding knowledge in Materia Medica. The growth in this field made it increasingly challenging to manually select appropriate remedies.

Hahnemann’s insight into the limitations of human memory in retaining vast amounts of information also played a significant role. He recognized the need for a systematic indexing system to manage the extensive data.

Another challenge was addressing similars. Hahnemann grappled with the question of how to effectively identify the most suitable remedy, or similimum, from a multitude of similar options.

Finally, the need for efficient retrieval of information was a crucial factor. Hahnemann acknowledged the difficulty in recalling all symptoms and the necessity for a tool to aid in quickly retrieving relevant information.

Hahnemann’s Cautions in Homeopathic Practice

In the book ‘Hahnemann’s Cautions’ by Guy E. Manning, M.D., San Francisco, California, several important points are highlighted regarding the practice of homeopathy.

Firstly, the importance of precision is emphasized. Homeopathic practitioners are urged to be exact, tireless, earnest, and diligent in their search for the appropriate remedy. This approach discourages guessing and settling for superficial symptom matching.

Secondly, Hahnemann criticized the limitations of repertories. He argued that they provide only “vague hints” rather than detailed guidance. This suggests that their usefulness is limited unless they are very detailed, which then makes them cumbersome and difficult to use.

Hahnemann’s Directive for Prescribing

Hahnemann provided a directive for prescribing remedies. The ideal approach involves carefully selecting remedies that holistically consider the patient’s mind, body, and soul. This ensures that the chosen remedy closely matches the symptoms, which counters lazy practices and leads to better outcomes.

Kent’s Perspective on the Use of Repertory and Materia Medica

According to J.T. Kent, a remedy that has been correctly worked out from the repertory should, when looked up in the Materia Medica, be perceived to agree with and fit the patient, his symptoms, his parts, and his modalities. He further stated that it is quite possible for a remedy not having the highest marking in the anamnesis to be the most similar in image, as seen in the Materia Medica.

Kent emphasized the role of the artistic prescriber, who sees much in the proving that cannot be retained in the Repertory, where everything is sacrificed for the alphabetical system. The artistic prescriber must study Materia Medica long and earnestly to enable him to fix in his mind sick images, which, when needed, will infill the sick personalities of human beings.

Furthermore, Kent pointed out that provings (MM) cannot be retained in the Repertory and that in the Repertory, everything is sacrificed for the alphabetical system, leading to the loss of the whole context. Therefore, the prescriber must study Materia Medica long and earnestly.

For instance, upon examining the longest rubric in Kent’s repertory, one may find that it lacks coherence. It is more beneficial to refer to the symptom in the Materia Medica for a comprehensive understanding. The process of creating the repertory and rubric often results in the loss of the entire context, thereby reducing its comprehensibility.

  • Chapter – COUGH
  • Rubric – LYING aggravation face, great rattling of mucus, which appears to be low down in chest, while cough does not seem to reach there, only to throat-pit, consequently hard cough does not reach phlegm unless he lie on his face when he brings up a greenish-yellow or a pale greenish- yellow gelatinous mucus without taste (313 alphabets)

Exercise:

To understand the shortcomings as asserted by the stalwarts. Let us try to understand how to build a Repertory from scratch?

(More than a doctor, it needs a language expert to write a repertory)

  1. Symptoms in the provings/materia
  2. Collect them/break them into smaller
  3. Convert into Rubrics (Repertorial language)
  4. Chunks

Now let us try to build a rubric by converting a symptom of Allen’s Keynote MM from symptom to rubric.

  1. Symptom: Before stool: rumbling, violent sudden urging; heaviness in rectum; during stool, tenesmus and much flatus; after stool faintness. – Aloe Socotrina

When converted to Rubric it becomes:

  • Stool, before, rumbling – Aloe Socotrina
  • Stool, before, urging, sudden, violent – Aloe Socotrina
  • Stool, before, rectum heaviness – Aloe Socotrina
  • Stool, during, tenesmus, – Aloe Socotrina
  • Stool, during, flatus, much – Aloe Socotrina
  • Stool, after, faintness – Aloe Socotrina
  1. Another example from Allen’s Keynote MM:
  • Symptom: Cannot go to sleep because she cannot get herself together; head or body feels scattered about the bed; tosses about to get the pieces together; thought she was three persons, could not keep them covered (Petr.). – Baptisia

When converted to Rubric it becomes:

  • Mind; delusions, imaginations; body, body parts; scattered about bed, tosses about to get the pieces together; tossing about bed to collect pieces – Baptisia

Exercise:

Now try to Search for common missing symptoms and drugs in repertory:

  • Cough as from smoke
  • Pain Mcburney
  • Traumatic neuritis
  • Painter colic
  • Lack of Interest
  • Beginning coryza (NV & Quillaya Saponaria- begining of coryza, frequently checking its further development.)

You won’t find them in the repertory. For finding them in the repertory you will have to undertake the whole exercise of converting the patient symptom into relevant rubric, it depends on the luck and the language capabilities of the physician to reach for such symptoms in the Repertory. Why take so much of pain and still having too low a probability of reaching the similimum.

Thus, the question arises: Why should we use the Repertory?

Repertory was Good: For pre computer era

Repertory is Good: Repertory is Good in one aspect that is Gradation of remedy according to clinical verification. But, this too can always be done for Materia Medica too.

What is the Solution?

  • Hahnemann emphasized the necessity for a tool to aid in quickly retrieving relevant information.
  • Kent pointed out that in the Repertory, everything is sacrificed for the alphabetical system, leading to the loss of the whole context.

Consequently, there is a need to develop an efficient retrieval tool, such as software, and to avoid indexation methods like alphabetical arrangement and chunking that sacrifice comprehensive understanding.

Advocating for a New Paradigm: Materiazation or Materiomics

There is a compelling case for a new paradigm in homeopathy, which can be referred to as Materiazation or Materiomics. This approach involves listing symptoms as they are presented in the Materia Medica, without converting them into rubrics, and then proceeding with gradation.

By making symptom analysis more intuitive and intelligent, semantic AI tools act as valuable assistants to homeopaths, enhancing decision-making without replacing the art of individualization.

The new concept of Semantic search, with the help of AI (artificial intelligence) and advanced computing technologies, offers a powerful tool to enhance remedy selection of remedies, how we retrieve and interpret complex information from Materia Medica.

  1. Understanding Intent Beyond Keywords: Traditional keyword searches often miss relevant remedies if exact terms aren’t used. Semantic search, powered by AI, understands the meaning behind the query, matching symptoms even if worded differently (e.g., “fear of death” vs. “dread of dying”).
  2. Contextual Symptom Matching: AI can interpret the context of a patient’s symptoms—physical, mental, emotional—and correlate them with remedies in a more human-like, accurate manner. This can mimic the approach of expert homeopaths who can read between the lines.
  3. Enhanced Remedy Differentiation: AI can compare similar remedies by analyzing their subtle distinctions across multiple Materia Medica texts. For instance, it might help distinguish between Aconite and Arsenicum Album in acute anxiety by examining emotional tone, modalities, and associated physical complaints.
  4. Faster, More Precise Repertorization: AI-driven semantic search can rapidly scan repertories and case notes to suggest possible rubrics and remedies that align closely with the case, thereby saving time and reducing oversight.
  5. Cross-Referencing Multiple Sources: AI can intelligently cross-link data from Hahnemann, Kent, Clarke, and others—bringing forth remedies that may be underutilized yet perfectly suited based on totality of symptoms.
  6. Case Pattern Recognition: With machine learning, AI can learn from large volumes of past cases to identify patterns and suggest likely remedies based on successful outcomes in similar situations.

AI plays a transformative role in calculating a similarity detection score between patient’s symptoms and those recorded in the Materia Medica, thereby assisting in selecting the most suitable homeopathic remedy with greater precision and objectivity.

  1. Symptom Vectorization: AI algorithms convert both the patient’s symptom narrative and Materia Medica symptom descriptions into mathematical representations known as vectors. This includes not just physical symptoms, but emotional and mental aspects, modalities, and concomitants etc.
  2. Similarity Scoring: AI then computes a similarity score—typically between 0 and 1—for each remedy, representing how closely the remedy’s known picture (from sources like Kent, Hahnemann, Allen) matches the patient’s totality of symptoms. A higher score indicates a stronger match.
  3. Weighting and Prioritization: The system can assign weights to different types of symptoms based on homeopathic principles—e.g., mental/emotional symptoms carry more weight than local physical symptoms, following Hahnemann’s guidelines on totality.
  4. Dynamic Comparison Across Authors: It can synthesize and compare symptom expressions across multiple authors like Boericke, Clarke, and Hering, allowing a more complete picture of the remedy to emerge.
  5. Visual Analytics: Finally, AI can present the results in user-friendly dashboards showing the top 5–10 remedies, their similarity scores, and matching rubrics—serving as a guide, not a replacement, for the homeopath’s final judgment.

In this way, AI helps quantify the qualitative process of individualization, aligning beautifully with Hahnemann’s vision of matching the remedy to the totality of symptoms.

This method offers several advantages over traditional repertorization. Firstly, it preserves the original context and detail of the symptoms, which can be lost when they are converted into rubrics. This ensures that practitioners have access to the full range of information about each symptom, enhancing their ability to select the most appropriate remedy.

Secondly, this format is highly conducive to training artificial intelligence (AI) and machine learning (ML) models. AI and ML have the potential to revolutionize homeopathy by automating and enhancing various aspects of practice, including symptom analysis and remedy selection. However, the effectiveness of these technologies is heavily dependent on the quality of the training data they are provided with.

By preserving the original, detailed symptom descriptions from the Materia Medica, the Materiazation approach provides rich, high-quality data that can be used to train more accurate and effective AI and ML models. This could lead to significant improvements in the accuracy and efficiency of homeopathic practice, ultimately leading to better patient outcomes.

Therefore, the adoption of the Materiazation or Materiomics paradigm could represent a significant step forward for the field of homeopathy.

Advantages of Materiazation or Materiomics:

  • Repertorization directly from Materia Medica.
  • No more sacrificing of Totality of symptom.
  • No more repertorizing and then the herculean task of cross verification in Materia Medica.
  • Symptoms (Rubrics) arranged in readable language for effective Materiazation or Materiomics (aka- repertorization).
  • Most things in this technique remains the same only the book changes from Repertory (Kent, BBCR,…etc) to Materiomics.

Simple yet powerful Materiazation or Materiomics technique:

  1. Patient presents symptoms
  2. Listen and write it down
  3. Search in MM
  4. Match patient symptom picture with Medicine symptom picture
  5. Prescribe
Repertorization Materiomics (Materiazation)
  1. Case Taking
  2. Analysis Of Case/Symptoms
  3. Evaluation Of Symptoms
  4. Totality Of Symptoms/Synthesis Of Case
  5. Selection Of Repertory according to the case
  6. Repertorize
  7. Repertorial Analysis
  8. Remedy Selection
  9. Go To Materia Medica And Check If The Remedy Is Really A Totality?
  10. Then Prescribe
  1. Case Taking
  2. Analyse for Totality Of Symptoms
  3. Materiomics
  4. Go To Materia Medica And Check If The Remedy Is Really A Totality?
  5. Then Prescribe

 

In conclusion, the advent of AI and advanced computing technologies in homeopathic medicine is paving the way for a future where traditional repertorization may become obsolete. By enhancing the efficiency, accuracy, and objectivity of the remedy selection process, AI will not only help in streamlining homeopathic practices but also enhancing the overall efficacy of treatments. As this technology continues to evolve, its integration into homeopathic science heralds a new era of precision and effectiveness, making personalized homeopathic treatment more accessible and impactful for patients.

Prof. Dr.Nisanth KM Nambison

  • Associate Prof. GHMC, Department of AYUSH, Govt of MP.
  • Ex-State convenor, M.P. Hemoglobinopathy Mission, National Health Mission, Ministry of Health.
  • Outgoing President, Telemedicine society of India, MP Chapter.
  • D (Hom.), MSc (Computer Science)
  • Stanford University School of Medicine – Certified for Artificial Intelligence and Health Care
  • IIT (Indian Institute of Technology), Roorkee, Certified for Machine Learning
  • IIM (Indian Institute of Management), Indore – Management Development Program

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