Multi-Similimum or Compartmental Method of Repertorization

Chandran Nambiar K C

Dr. Samuel Hahnemann says in his Organon of Medicine:
Aphorism 2: “The highest ideal of cure is rapid, gentle and permanent restoration of the health, or removal and annihilation of the disease in its whole extent, in the shortest, most reliable, and most harmless way, on easily comprehensible principles”.

Medicine, Aphorism 3: “If the physician clearly perceives what is to be cured in diseases, that is to say, in every individual case of disease (knowledge of disease, indication), if he clearly perceives what is curative in medicines, that is to say, in each individual medicine (knowledge of medical powers), and if he knows how to adapt, according to clearly defined principles, what is curative in medicines to what he has discovered to be undoubtedly morbid in the patient, so that the recovery must ensue- to adapt it, as well in respect to the suitability of the medicine most appropriate according to its mode of action to the case before him (choice of the remedy, the medicine indicated), as also in respect to the exact mode of preparation and quantity of it required (proper dose), and the proper period for repeating the dose; – if, finally, he knows the obstacles to recovery in each case and is aware how to remove them, so that the restoration may be permanent, then he understands how to treat judiciously and rationally, and he is a true practitioner of the healing art”

Aphorism 7: “Now, as in a disease, from which no manifest exciting or maintaining cause (causa occasionalis) has to be removed1, we can perceive nothing but the morbid symptoms, it must (regard being had to the possibility of a miasm, and attention paid to the accessory circumstances,) be the symptoms alone by which the disease demands and points to the remedy suited to relieve it – and, moreover, the totality of these its symptoms, of this outwardly reflected picture of the internal essence of the disease, that is, of the affection of the vital force, must be the principal, or the sole means, whereby the disease can make known what remedy it requires – the only thing that can determine the choice of the most appropriate remedy – and thus, in a word, the totality of the symptoms must be the principal, indeed the only thing the physician has to take note of in every case of disease and to remove by means of his art, in order that it shall be cured and transformed into health”.

According to Dr. Samuel Hahnemann, the highest ideal of a physician is to get a “rapid, gentle and permanent restoration of health”of his patient “on easily comprehensible principles”. To be “a true practitioner of the healing art”, the physician should “clearly perceive what is to be cured in diseases”, “what is curative in medicines”, and how to adapt, the “curative” to the “to be cured”. He should also know the “exact mode of preparation and quantity”, “proper period for repeating the dose” and how to remove “obstacles to recovery”. Except the possiblity of any “exciting or maintaining cause”, “a miasm”, and “accessory circumstances”, nothing but the “morbid symptoms”, should be considered by the physician,  and “totality of symptoms”, should be the sole means to “determine the choice of the most appropriate remedy”.

Logic of “Multi-Similimum” or “Integral Similimum”:
“Multi-Similimum” method of repertorization or “Integrated Similimum, a well-principled  improvisation in modern homeopathic practice, is the most effective and rational way of attaining “total cure” of the patient.  It is an enirely new concept, evolving as a logical outcome of the scientific understanding of homeopathy, similia similibus curentur, potentization, life, disease and cure, as proposed in my article on DIALECTICAL HOMEOPATHY. It clearly perceives “what is to be cured in diseases”, “what is curative in medicines”, and how to adapt, the “curative” to the “to be cured”. In order to determine the choice of the “most appropriate remedy”, it solely relies up on “totality of symptoms”, with due considerations given to any “exciting or maintaining cause”, “a miasm”, and “accessory circumstances”.

“Multi-Similimum” method is not at all a shortcut to bye-pass systematic case taking, anamnesis  and repertorization that  require much intellectual input and hard work. The concept of “multi-similimum” is the integral part of a scientific understanding of “total personality” of an individual patient. In this method, symptoms collected through elaborate and systematic case taking are “compartmentalized” into various  individual symptom groups, called “symptom complexes”, and separate similimum determined for each “symptom complex”. Drugs thus selected are combined to prepare a  “integrated similimum” applicable for the particular patient. If perfecty worked out, this “integrated similimum”  will act as a holistic “single drug”, containing all the diverse types of “molecular imprints” capable of removing each and every molecular blocks, and rectifying all the pathological bio-chemical deviations of the vital processes in the particular organism.

What is “to be cured” in diseases? Instead of vainly repeating the vitalistic explanations provided by our old masters, we should be ready to accept the scientific perception of diseases as specific molecular errors in the vital processes. In most instances of pathology, these molecular errors happen due to the binding of some endogenic or exogenic foreign molecules up on complex biological molecules, thereby resulting in deviations in biochemical pathways. Cure consists of removal of these molecular errors in the organism. Therapeutics is the art of removing these molecular errors by using appropriate medicinal substances.

What is “curative” in homeopathic potentized medicines? Potentized homeopathic medicines  contain different types of 3-d nano-cavities or “molecular imprints” formed in water-alcohol matrix, by imprinting with the individual constituent molecules of drug subastances used for potentization. These “molecular imprints” are capable of binding to the pathological molecules having a configurational similarity to the original drug molecules used for “imprinting”. Such a binding will result in the removal of molecular blocks, thereby relieving the biological molecules from pathological inhibitions.

How to adapt the “curative” to the “to be cured? The “curative” factors are selected and applied to the “to be cured” according to the homeopathic principle of “similia similibus curentur”.

How to determine the choice of “most appropriate” remedy? According to my interpretation,  “most appropriate” remedy should contain all the diverse types of “molecular imprints” required to remove all the molecular errors in the particular organism. As per the proposed method, “molecular imprints” appropriate for each individual molecular error should be separately determined and “integrated” into making of a most appropriate “single remedy”.

How the concept of “totality of symptoms” is perceived? Each specific molecular error in the organism expresses as a particular train of subjective and objective symptoms called “symptom complexes”, with peculiar locations, sensations, modalities and concomitants of their own. Totality of all these separate “symptom complexes” constitute the “totality of symptoms” of an individual. Such a totality  comprises of all the diverse “symptom complexes” representing all the genetic, constitutional, miasmatic and acquired molecular errors in that individual.

“Multi-Similimum” method and “Multiple-Drug Prescriptions”:
A word of caution. When I talk about  “Multi-Similimum” method of repertorization  or “Integrated Similimum” as a powerful clinical strategy that should be adapted in homeopathy, many homeopaths may at first glance think that I am arguing in favor of unprincipled random mixing of drugs for each and every particular disease entities, as done by the manufacturers of patent combinations now flooding the homeopathic market and blindly prescribed by many homeopaths. I am not at all for such generalized combinations of homeopathic drugs. I am proposing a systematic method of preparing a “Integrated Similimum” for the particular patient we are dealing with, and such a “drug” will never be appropriate for another individual. More over, “Multi-similimum method of repertorization”  or “Integrated Similimum” should not also be confused with  “multiple drug prescriptions”. “Multiple drug prescriptions”  are commonly employed when the prescriber  is not much confident regarding the selection of similimum in a given case.

For most people engaged in this method, it almost develops in time into a habit of prescribing  multiple drugs even in very simple cases. Perhaps  he may not be able to take a final decision between two seemingly similar drugs. This may also be due to paucity of well marked reliable symptoms, non-co-operation of patient, inappropriate case taking, wrong repertorization, deficiency in materia medica knowledge, or aversion to work hard to find a similimum. Perhaps the case may be so acute and severe that it demands instant palliation. In such cases, the doctor may be compelled to use more than one drug, which seems to be equally indicated. Of course, if the real similimum is included  in such a multiple drug prescription, it will definitely act and patient will get relief. If you are using potencies above 23c, since they contain only ‘molecular imprints’ of drug molecules, according to my perception, there will be no any chance for interaction  between drugs. Hence, there is no any particular harm in using this method, other than the fact that the patient get only partial cure, and it may also be difficult to ascertain which drug actually worked, so that we will have to repeat same combination of drugs if follow up is required. This method of “multiple drug prescription” is used by many homeopaths at least in certain clinical contingencies.

My propositions  regarding “Multi-Similimum” naturally evolve as the logical extension of my scientific concepts regarding “potentization” as a technology of “molecular imprinted drug designing”. I usually recommend only potencies around 30c, and consider it unhomeopathic to use drugs in low potencies(below 23C) that may contain drug molecules.  I am talking only about the desirability of combining of drugs selected as similimum through correct case taking, strict individualization and scientific “compartmentalized” repertorization for each individual patient. More over, this idea is very much in conformity with the modern understanding of diseases as deviations of vital processes arising from some or other molecular errors in the organism. According to my perspective, an individual may be having different types of molecular errors in different biochemical pathways caused by entirely different molecular blocks, and represented in the form of different groups of subjective and objective symptoms. A particular ‘symptom group’ may be the expression of a particular molecular error in a particular bio-chemic pathway, where as another “symptom group” may be representing an entirely different molecular error. Expecting a ‘single’ drug to cover all these diverse and unrelated “symptom groups” representing entirely different types of molecular errors in an organism is obviously utopian wishful thinking. Since different molecular errors may be caused by the binding of different types of exogenic or endogenic foreign molecules upon different biological molecules and pathways, we have to find appropriate ‘similimum’ for each “symptom group” to effect a complete cure. Otherwise we get only partial cures.

“Multi-similimum” method is based on the scientifc understanding that “symptoms”, whether subjective or objective, are the expression of certain pathological deviations in some biochemical pathways in the organism, caused by some or other molecular errors. Deviations in a particular biochemical pathway produces a given group of symptoms consisting of peculir locations, sensations, modalities and concomitants(LSMC). Deviations in different biochemical pathways produce different groups of symptoms, which we call “symptom complexes”. Each “symptom complex” represents a particular biochemic deviation, caused by a particular molecular error. This is applicable also to symptoms that we call “constitutional” and “miasmatic”. Constitution and “miasms” of an individual is determined by different kninds of diverse genetic or acquired molecular errors.

Different pathological deviations in vital processes happening at molecular level  are expressed in the form of different  subjective and objective “symptom complexes”. No body with a rational mindset can deny the fact that we  cannot find a “single drug’ that covers all those diverse “symptom complexes”  in their “totality”expressed by an individual. It is obvious that a “single drug” of our materia medica cannot contain all the ‘molecular imprints’ required for correcting all these diverse molecular errors existing in the  organmism. Hence, a single drug, how much “similimum” we think it to be, can never cure a patient completely. A drug selected as “similimum” through our existing methods may rectify only a few molecular errors expressed as some of the prominent “symptom complexes”. To effect a complete cure, we should administer a drug that contain all the different types of ‘molecular imprints’ that can rectify all the pathological molecular deviations in that person. Since it is obviously impossible to get such a single drug from nature, we have to prepare a “single drug” that contains all the required molecular imprints for our particular patient. This process is called “integrating similimum”. In this process, we select separate drugs for different “symptom complexes” and mix them together to prepare a single “similimum” that holistically covers all the “symptom complexes”, or “totality of symptoms”. This is the essence of “multi-similimum” concept.

How to apply “Multi-Similimum Method:
I would suggest to attempt “multi-similimum” method only if the physician has enough time to spare on a case. To work out a case as per this method, a detailed and systematic case taking is mandatory. No symptom should be ignored or omitted. Each symptom should be explored in its every details such as locations, sensation, modalities and concomittants(LSMC). For instance, if our patient complains headache, record that with all associated details of LSMC. If same patient complains about some skin eruptions, that also should be recorded with its LSMC. Then there may be abdominal symptoms, mental symptoms, physical generals and the like. Record everything in detail with LSMC.

Once the case taking is completed, next important step is to arrange those symptoms into appropriate “symptom complexes” or “compartments”. This should be done with utmost diligence. Each major symptom, with its qualifying details of locations, sensations, modalities and concomitants  may be grouped under a particular “symptom complex”. Theoretically, “a symptom complex” represents a whole train of symptoms representing a specific pathological deviation in a particular bio-chemical pathway in the organism. Hence, scientific knowledge of pathology and molecular biochemistry would help the physician a lot in undertaking this task effectively. You may need a second interview with the patient to get some more details during this “compartmentalization” process. When such systematic “compartmentalization” of symptoms is done perfectly, we can go for  the actual repertorization.

Now we have to find appropriate repertorial rubrics for the symptoms. Repertorize each “symptom complex” separately and find its similimum. Ideal similimum will be the drug that covers all individual rubrics being part of the “symptom complex”. Most probably, for each “symptom complex”, we will get a separate similimum. If same drug happens to be similimum for more than one “symptom complex”, that should be welcomed as a positive indication. Prepare a “similimum list” of all the drugs selected through repertorization of different “symptom complexes”.

If there are any uncommon, peculiar, characteristic symptoms in the case, not part of any particular “symptom complex”, consider such symptoms as separate individual “symptom complex”, and add their similimum  also to the “similimum list”.

Then consider indications for any nosodes, sarcodes  and other “miasmatic” drugs. They may not come from repertorization, as our reprtories do not represent symptoms of such drugs sufficiently. Tuberculinum, medorrhinum, Thyroidinum, Adrenalin, Pitutrin, and such other drugs will never come top in repertorization. Hence if they come under any of symptom groups, even though not at the top level, they should be added to the similimum list. Perhaps we will have to consider such drugs merely on the basis logical thinking based on our knowledge of biochemistry and molecular pathology. “Causation” also will have to be considered in this way. Causative drugs never come top in repertorization. So they also should be given special consideration.

Now our final “similimum list” is ready. Do not bother much  about the number of drugs. On the other hand, it is very important that any drug which may have a role to play should not be omitted. Procure the drugs from most trusted sources only. Mix them in equal quantities in 30c potency to prepare the “Integrated Similimum” for that particular patient.  If we have done the work perfectly, such a preparation presumably will contain all the “molecular imprints” that may be required to remove all molecular blocks in that patient. By administering this “single drug” for appropriate period, we can ensure a “total” cure for the patient.

Dose, repetition and mode of administration are for the physician to decide. I give three times a day in acute conditions, and once daily in chronic cases, until complete cure is reported. Dose is decided on the basis of number drugs contained in our preparation. A ‘drop for a drug” is my law. If the “integrated-similimum” is prepared by adding five drugs, I use 5 drops for a dose.  There is no harm if you increase or decrease the quantity. It will work.

“Multiple Drugs” Vs “Single Drug”:
I am well aware that homeopaths generally consider prescribing of more than one medicine at a time, simultaneously, alternating or mixing with each other is totally unscientific, un-principled and un-homeopathic practice. Of course, they may quote extensively from our great masters as supporting evidences for their opposition to multiple drugs. If one is any way constrained to prescribe multiple drugs in certain compulsory practical contingencies, it is done with a conscience of guilt as if he is committing a grave sin to the “sacred” system. They shy to admit it openly, and try to cover up what have been done. The theory of ‘one medicine, one dose’ is considered to be the golden homeopathic rule, and everybody strive to convince others that he is an ardent follower of this rule. People who claim to follow the ‘one medicine, one dose’ rule are held in high esteem by the profession, as true “classical homeopaths”.

We have to examine this “single drug versus multiple drug” issue with honesty and a rational scientific mindset. We should understand that there a lot of relatively darker areas in homeopathy, and obviously a lot of unanswered,incompletely answered and wrongly answered questions there. Once the fundamental principles are scientifically explained, it will be easier to sort out such lesser issues logically.

Is it acceptable in homeopathy to prescribe more than one medicine at a time? Is it against the fundamental logic of homeopathy to do so? Whatever our great masters have said earlier within the limitations of their space-time context, we will have to make a rational assessment of certain factors while trying to answer this important question on the basis of updated knowledge.

In homeopathic terminology, any form of drug substance used as a sample for “proving” is considered to be a single entity. It is called a ‘single drug’, even though it may be a complex mixture of several substances. For example, an alcoholic tincture extracted from the Nux Vomica plant is evidently a mixture of many types of enzymes, alkaloids, glycosides, phytochemicals, and other organic and inorganic molecules. Over and above the natural organic contents, various elements and chemical molecules absorbed from the environment will also be part of that tincure. It may also contain various accidental contaminants and pollutants also. In spite of all these possibilities, we consider Nux Vomica tincture is a “single” medicinal substance, and we often talk about a “Nux Vomica personality” as such!

When we introduce a sample of Nux Vomica tincture into the living organism for ‘proving’, its constituent molecules are instantly subjected to various processes such as disintegration, ionization, hydration and certain chemical transformations. Individual constituent molecules are carried and conveyed through blood and other internal transport systems into the cells in different parts of the body. They interact with various enzymes, receptors, metabolites and other biological molecules inside the organism. These interactions are decided and directed by the specific properties such as configurataion and charge  of active groups of individual drug molecules, and their specific affinity towards biological target molecules. It is very important to note that Nux Vomica interact with different biological molecules, not as a singular entity, but as individual constituent molecules and ions. These individual drug molecules and ions are capable of binding to some or other biological molecules, effecting configurational changes in them, and thereby inhibiting the essential bio-chemical processes which can take place only with their presence and mediation. Such molecular inhibitions in various bio-chemical pathways result in a condition of pathologiy, expressed as a train of subjective and objective symptoms, due to the involvement of various neuro-mediator and neuro-transmitter systems.

The symptoms we get from the proving of Nux Vomica are in reality the results of diverse deviations in different bio-chemical processes and pathways, created by the constituent drug molecules in their individual capacity and specific configurational affinity. Each type of molecules contained in Nux Vomica binds only to a specific group of biological molecules, and creates their own individual groups of symptoms. Suppose we could completely remove all molecules of a particular alkaloid from a sample of Nux Vomica before it is used for proving. Naturally, during the process of proving, we shall be missing the groups of symptoms that should have been created in the organism by the molecules of that particular alkaloid. This type of proving may be called ‘differential proving’. By conducting such differential provings, we can learn about the particular state of pathology that may be attributed to individual constituent molecules contained in each medicinal substance. More over, this type of scientific differential provings may be utilized to study the biological effects of various constituent molecules of drug materials that we erroneously consider as single drugs. Such differential provings may disprove our mis-conceptions regarding ‘single drug’, at large. This is a subject that warrants serious attention from the part of homeopathic researchers and research institutions.

There are a few more points to be considered in association with the issue of ‘single drug’. Chances of drug samples used in proving being contaminated with various environmental particles and foreign molecules should be seriously considered here. Especially in the olden days of most of the drug provings, our knowledge regarding environmental pollutions and contaminations was very limited. During drug proving, molecules of such contaminants also would have obviously undergone proving, along with original drug molecules. Especially for homeopaths, who are convinced about the power of micro doses, this factor cannot be overlooked. The water, alcohol, sugar of milk etc., used in the process of preparing drugs for proving may also have various contaminants. The vessels, utensils, equipment, tools, air, and provers themselvs also may add their own contaminations. These contaminants and impurities also would have been subjected to proving along with original drugs, and their symptoms also included in our materia medica unknowingly, although we don’t take these factors seriously into account. We should be aware of the fact that the biological deviations created in the prover by these un-recognized foreign molecules are also included by us in the accounts of medicinal substances used for proving. It means that at least some of the symptoms we learn in the Materia Medica of a drug may not be actually related to that drug at all, but to the contaminants. This issue will have to be considered in more details later, when discussing about ‘materia medica’.

It is not at all realistic to imagine that the same drug sample of Nux Vomica used for proving is always used for preparing its potencies also. It may have been procured and prepared from another location, climate, environment, time and circumstances. All of these factors may necessarily influence their chemical constitution also. Contaminants and pollutants also differ with time, place and persons who handled it. Yet, we are obliged to call all these different samples as Nux Vomica, and use it as same drug, believing that it is a ‘single drug’!

In reality, potentized Nux Vomica we get now from pharmacies are prepared from samples very much different from the samples used for proving it two hundred years back. It might not necessarily be the same contaminations and foreign molecules which happen to be mixed with the drug during procurement and potentization. Entirely new type of impurities and foreign molecules, different from proven samples, shall definitely get mixed with drugs while potentizing. Naturally, these contaminants and foreign molecules also get subjected to potentization along with original drug molecules. It is evident that the homeopathic potencies of Nux Vomica we get from pharmacies contain the potentized forms of these new contaminant molecules also. In other words, they are mixed with potentized forms of these unknown substances, entirely different from those were subjected to proving. We cannot ignore the fact that we are not using potencies of same drug, that have been proved earlier and recorded in the materia medica, eventhough we call it with same name. It is composed of an entirely different mixture, much more different in molecular structure from the one subjected to original proving. We use the potentized form of this new combination, on the basis of symptoms produced by another combination earlier, using the therapeutic principle ‘Similia Similibus Curentur’. Is not this realization somewhat embarassing? Unless we provide convincing solutions to the ethical, theoretical and practical problems raised by this situation, it would be unfair to continue claiming that we are using ‘single drugs’!

The following facts are evident from this deliberation. At least some or other groups of symptoms attributed in the Materia Medica as that of a particular drug substance used for proving might not be related to it at all, but to the contaminants happened to be subjected to proving. Same way, in the potentized form, we are administering to the patient potencies of some additional molecules also in the, entirely different from those subjected to earlier provings. In short, Nux vomica we read in materia medica is different from Nux Vomica we use for treatment, even though both bear the same label. It means that while there will be most of the expected qualities in the potencies we use, there will definitely be the absence of at least some or other qualities we expect. Because, certain contaminant molecules subjected to proving and represented in the materia medica, might not be present in the samples used for potentization. It shows how much uncertain and unpredictable is the outcome of homeopathic medication in present situation.

Now, we have to consider the factor of foreign molecules which are likely to contaminate unexpectedly into the samples used for the commercial preparation of potencies. These foreign molecules have never been proved. We are totally ignorant about the different ways in which they might have interacted with the molecules of the original drug. We have no idea regarding the molecular inhibitions or the groups of symptoms they are likely to produce in the living organism. Inspite of all these deficiencies, we apply the potencies of such unknown foreign molecules also, along with the original medicinal substance in to the body of a patient. Same time, we claim we are using ‘single drug’ only!

During our clinical practice, we would have experienced instances of removal of totally unexpected symptoms and diseases from the patient. Those symptoms might not be included in any text book of Materia Medica of the given drug. I suspect it may be the potencies of those unknown molecules entering the sample during potentization that is playing this trick.

The above facts more than expose the hollowness of our belief and often-repeated claim that we give a ‘single medicine’ to our patient. It is undeniable that we are using medicines selected on the basis of similarity of symptoms, mixing it with potencies of some or other different types of molecules  as well. This is an unpleasant situation which we cannot neglect. We should understand that we are giving the patient a mixture of potencies of different types of molecules, about some of which we have no idea at all. Same time, our medicines provide expected results when applied on the basis of ‘similia similibus curentur’. It shows that the presence of potencies of any unproved and unknown foreign molecules in the potentized drug in no way negatively affect the its effectiveness as a therapeutic agent.

During proving of drugs, the molecules and ions contained in them act individually up on different bio-molecular targets, on the basis of their configurational and charge affinity, and produce their own individual “groups of symptoms”. Like wise, when drugs are potentised, the constituent molecules and ions are individually subjected to a process of molecular imprinting in water-alcohol mixture, forming hydrosomes, that are exact counteractive configurational factors (CCF) of original molecules used as “guest” molecules in imprinting. That is why the presence of impurities which enter at the time of potentisation never adversely affect the quality of the potencies of original drug. All the potencies, that we consider as single medicine are in realty a mixture or combination of “molecular imprints” of different types of independent molecules and ions, which never interact with each other in potentized form. This revealation prove that there is no harm to the “molecular imprints” of original drug molecules contained in the potencies, even if potencies of any foreign molecules happen to be mixed with them, deliberately or otherwise. More over, when introduced into the organism, these “molecular imprints” interact with biological molecules in their individual capacities, on the basis of configurational affinity. Since molecules and ions are subjected to molecular imprinting in their individual capacities, and they cannot interact with each other in that form, there is no chance of happening any harm, by mixing two or more samples of potencies of different drugs.

There is least possibility of any constituent molecules of drug substance remaining in their potentized forms above 23c. Only molecular imprints will remain. Hence, when higher potencies of two drugs are mixed together, there will be no chemical interaction taking place between them. In such a mixture, the molecular imprints of constituents of both samples will remain independent, without influencing each other, and with out losing their own individual qualities whatsoever.

What happens when such a mixture of two or more potentized drugs is introduced into the organism of a patient? Naturally, the molecular imprints of each constituent drug molecule interacts with biological molecules and pathological molecules individually, based on their specific configurational affinity. As counteractive configurational factors, they can bind only to the pathological molecules, which are similar to the original drug molecules that were used for imprinting. The biological molecules are thereby relieved from inhibitions caused by pathological molecules. This process ultimately removes the state of pathology, and relieves the subjective and objective symptoms of disease. A homeopathic cure is said to be effected. Due to their specific configuratioanal affinity, each type of molecular imprints can locate, identify and bind to exact molecular targets, whereas in the absence of exact molecular targets, these imprints stay neutral, since they are composed of mere water and alcohol molecules. The saying that ‘if a homeopathic potency is not similimum to a patient, it will not act’ is well explained here.

The qusetion of acceptability of administering two or more homeopathic medicines in potentized form, by mixing, alternating, or simultaneously, should be discussed in the light of the above findings.

It is a very important fact that the drugs in the potentized form, which have no similarity with any group of symptoms shown by the patient, will not be able to create any sort of reaction in the living organism. Chemically, potentized drugs being only a mixture of alcohol and water, their chemical properties will remain confined to that molecular structure. Therefore, when we mix homoeopathic potencies of different drugs together, there is no chance for any chemical interactions to take place. More over the configurational properties of the diverse types molecular imprints contained in them are not in any way destroyed by this mixing.

Issue of “Drug-Relationships:
“Drug relationship” is a subject about which most homeo practitioners are very much worried and confused when talking about combining of potentized drugs. Some practitioners very much rely upon ‘drug relationships’ even in deciding their treatment protocols. Concepts such as ‘complementary’, ‘inimical’, ‘antidotal’ etc., are frequently utilized in everyday practice. Some doctors even deviate from the theory of similimum, due to their over indulgence with ‘drug relationship’ protocols. When prescribing a drug based on its so-called complementary relationship to the earlier prescriptions, we forget to consider whether it is a similimum by totality of symptoms. Yet, we call it ‘classical’ homeopathy. When searching through the literature and authorities regarding drug relationships, it will be seen that no reliable scientific studies have been done on this subject. Most of the drug relationships are proposed by empirical clinical observations of practitioners, and not corroborated by scientific studies or evidences. More over, practitioners who are not much bothered over this relationships between drugs swear that their experiences prove otherwise. Some homeopaths prescribe even so-called inimical drugs simultaneously or alternatingly, and get expected positive clinical results.

We have already seen during our previous deliberations that in homeopathic potencies above 23C, there is no chance of drug molecules to exist. These preparations contain only molecular imprints of constituent molecules of the drug substance subjected to potentization. Molecular imprints are only supramolecular formations or hydrosomes. Chemically, they contain only water and ethyl alcohol molecules. Any sample of potentized homeopathic drug contains hundreds of types of individual “imprints”, representing the diverse types of molecules contained in the original drug substance. It is clear that they co-exist without disturbing or influenzing each other in anyway, same time preserving their individual properties as “molecular imprints” of specific drug molecules.

  1. This clearly indicates that highly potentized homoeopathic preparations cannot interact with each other , since they contain no drug molecules. Obviously, they are not likely to engage in any mutual interaction within or outside the organism. They can never antidote or destroy each other.
  2. Same time, the case of mother tinctures and preparations below 23c potencies may be totally different. They contain crude drug molecules, which can interact with each other due to their chemical properties. The concept of ‘drug relationships’ may be valid in the case of these low potencies. Low potencies may be more active than crude drugs, since they contain free molecules and ions.
  3. Low potencies and mother tincture of a drug may antidote higher potencies of same drug, due to the interaction with the counteractive complementary factors(CCF) contained in the higher potencies.
  4. Same way, low potencies and mother tinctures of a drug may antidote higher potencies of another drug that may contain similar constituent molecules, due to the interaction with the counteractive complementary factors(CCF) contained in the higher potencies. Obviously, drugs containing similar molecules may have more or less similar symptomatology during drug proving.
  5. Higher potencies of a drug may antidote the physiological effects of low potencies and mother tinctures of same drug, due to the interaction with the counteractive complementary factors(CCF) contained in the higher potencies.
  6. Same way, higher potencies of a drug may antidote low potencies and mother tincture of another drug, that may contain similar constituent molecules, due to the interaction with the counteractive complementary factors contained in the higher potencies.

If there is similarity only between certain types of constituent molecules of two drugs, partial antodoting is possible. That means, molecules having configurational similarity only are subjected to antidoting by this way. Such drugs will have partially similar symptomatologies also.

We should be aware of the possiblity of dangerous chemical interactions that might result between the constituent drug molecules of different drugs, when we mix or administer two or more mother tinctures and low potency preparations together.

To conclude, there is no harm in mixing together, alternating or applying simultaneously, any number of potentized homoeopathic drugs above 23c. As such, there is no need of any guilty feeling on the part of homeopaths who practice this method. They need not shy away from declaring this fact openly, fearing that it is unscientific.

In my opinion, “multi-similimum”  or “compartmental” method is the real homeopathy which takes into account the “totality of symptoms” of the patient in its real sense. This “multi-similimum” or “integrated similimum” may  be considered as the “single drug” appropriate for the “totality” of  that particular patient, only which can fulfill the “rapid, gentle and permanent restoration of the health, or removal and annihilation of the disease in its whole extent, in the shortest, most reliable, and most harmless way, on easily comprehensible principles”, which our Master conceived as  “the highest ideal of cure”. (As updated on 15-10-2010)

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Chandran Nambiar K C
Developer: Similimum Ultra Homeopathic Software
Mob: 919446520252

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