Kavya K.S, Dr Mansoor Ali
1.PG Scholar, Govt. Homoeopathic medical college, Kozhikode
2. Associate Professor, Govt. Homoeopathy Medical College, Calicut
Dyslipidemia is a major cause of cardiovascular disease, which in turn, is the most common cause of female morbidity and mortality.1 Menopausal transition is characterised by decline in oestradiol which causes increase in the total cholesterol (TC), low-density lipoproteins(LDL-C) levels, triglycerides(TG) and a decline in the high density lipoproteins which increases the cardio vascular risks.2 It has been reported that postmenopausal women are four to eight times more likely to die of CAD than of any other disease targets3. So the menopausal health demands higher priority.
Side effects of conventional treatments for dyslipidemia are better known today.4 Although the effectiveness of homoeopathic medicines in dyslipidemia is proved by few clinical and pre clinical studies5 but the previous studies did not focus on the management of dyslipidemia in menopausal women and also there is no exact reportorial representation in synthesis repertory.6
Methods: A prospective study was conducted in randomly selected 30 postmenopausal women with elevated cholesterol in fasting lipid profile attending the outpatient and inpatient departments of Government Homoeopathic Medical College, Kozhikode affiliated to Kerala university of health Sciences(KUHS), Thrissur. The selection of medicine, potency and repetition for each case was strictly according to the homoeopathic principles through the process of repertorisation using 9.1 version of Synthesis repertory.5 The assessment of treatment was made by a scoring based on ATP III guidelines on dyslipidemia using paired t test.
Results: The maximum prevalence of dyslipidemia in the study was noted in the age group 55- 59 years. Out of 30, 83% were with natural menopause, 33% shows positive family history, menopausal hot flushes were present in 33%. Presenting symptom in about 50% patients were palpitation of heart, in 23.3% as weakness of body.
60% cases shows significant improvement and 10% remained static and the remaining 30% showed slight aggravation. Homoeopathic medicine Phosphorus found to be effective in 30% cases and Natrum Mur in 23% cases. The potencies found useful were 200 and 1M. Statistical analysis was done using paired t test and this study was statistically significant.
Conclusion: The study shows that homoeopathic medicines selected by repertorising with Repertorium Homoeopathicum Syntheticum by Dr.Frederik Schroyens were effective in the management of dyslipidemia in menopausal women. This study also facilitates better understanding about dyslipidemia in menopausal women. As this is a lifestyle disorder co- operation from patient in dietary and lifestyle intervention is mandatory.
Key words: Dyslipidemia, Menopausal women, Synthesis repertory, Lipid profile.
- Mariam MBB, Devi Usha. The Prevelence of Dyslipidemia among Postmenopausal Women in Bangalore (Urban Area). IJETST 2016; Vol.03 Issue3 .Pages 3718-3724
- R.K. Swapnali, Kisan R, Murthy J. Effect of Menopause on Lipid Profile and Apolipoproteins
- Van der Schouw YT, Van der Graaf Y, Steyerberg EW, Eijkemans JC, Banga JD. Age at menopause as a risk factor for cardiovascular mortality. Lancet Lond Engl. 1996 Mar 16;347(9003):714–8.
- ThompsonDpaul,Panza Gregory,Zaleskai Amanda.Statin associated side effects.JACC.2016.67(20)
- Rupali D Bhalerao, Raj K Manchanda, Varanasi Roja. Homoeopathy in the management of Dyslipidemia: A short review. IJRH. 2015;9(4):258–66.
- Schroyens Frederik. Repertorium Homoeopathicum syntheticum. 9.1. Newdelhi: Bjain; 2014