Homoeopathic medicine Ignis alcoholis in subclinical hypothyroidism -a case report

Dr Jesiah Anto Poovendan

Hypothyroidism is second most common endocrine disorder worldwide, occurring due to deficiency in circulating thyroid hormones. Subclinical hypothyroidism(SCH) characteristically presents with normal thyroxine (T4) levels and elevated thyroid stimulating hormone (TSH) levels. According to a recent Indian study , SCH prevalence was 24.7% and showed a higher prevalence in the older population aged between 61 and 70 years(38.5%).

A female aged 26 presented  with complaints of hair fall, tiredness, constipation, weight gain, diagnosed as subclinical hypothyroidism, based on investigation. An individualized Homoeopathic medicine IGNIS ALCOHOLIS was selected and prescribed for the patient, on the basis of totality of characteristic symptom and analysis by repertorization. TSH levels were investigated and analyzed before and after treatment.  Post treatment analysis was done using Modified Naranjo Criteria for Homoeopathy (MONARCH ), which determines the causal attribution of clinical outcome after the Homoeopathic intervention. During the period of  5 months, the patients symptoms completely subsided and the TSH  levels were maintained within normal limits. So this case is helpful in analyzing the effectiveness of individualized Homoeopathic medication in treating sub clinical hypothyroidism.

A female patient aged 26 reported to our outpatient department with complaint of hair fall in bunches

and tiredness since many years. Constipation, passes 2- 3 days once. Weight gain from 61 kg to 65 kg within 2 months. Headache since 12 std, especially in occiput extending to neck and shoulder with nausea and aggravated on, sun exposure, bright light on and off. Better on, sleeping in dark room.


  • Appetite-good, can tolerate hunger, eats thrice a day at regular intervals
  • Thirst- decreased, drinks 1-2 liters , very little amount at long intervals
  • Sleep- 1am-9am, unrefreshed sleep
  • Stool- constipation passes stool 2-3 days once in morning
  • Urine – yellow , no odour, no difficulty , passes 4 times in morning and 2 times in night
  • Perspiration-scanty , no odour, no sediments
  • Dreams-bats flying in sky++, rats(roaming)in ground


  • Lmp-20/7/2023
  • Regular menses, no leucorrhoea
  • Dysmenorrhea on and off
  • Before menses, bilateral ankle pain with swelling, better during menses


  • Aversion to criticism
  • Aversion and gets anger being questioned when anyone interrupt her++
  • Anger if anyone finds faults on her
  • Image conscious
  • Desire appreciation++
  • Fear of insects and lizards+++
  • Aversion animals++


  • Rep dt- 1/7/2023
  • Ft3-2.85
  • Ft4-0.90
  • Tsh-16.830

Based on symptomatology and correlation with laboratory reports she was diagnosed as subclinical hypothyroidism


kentian method of evaluation was selected and totality of symptoms were constructed, as it contains , striking, prominent, mentals and physical generals.

  • Dreams-bats flying in sky++,rats roaming in the ground
  • Desire appreciation++
  • Fear of insects and lizards+++
  • Aversion animals
  • Thirst- decreased, drinks very little amount at late intervals
  • Constipation in morning
  • Dreams-bats flying in sky++,rats roaming in the ground
  • Perspiration-scanty
  • Hair fall
  • Tiredness
  • Hypothyroidism


  • Mind- animals- aversion
  • Dream- bats- invading out of the sky
  • Dream- rats
  • Mind- fear insects of
  • Glands- thyroid gland-general- hypothyroid
  • Head- hair- falling-handful of
  • Rectum -constipation- accompanied by-straining
  • Perspiration- scanty -sweat


  • SEPIA- 5/4
  • NATRUM MUR-5/3
  • PHOS-5/3

Using radar software and after repertorization, and in reference with materia medica, IGNIS ALCOHOLIS was selected as similimum for this patient , as it covered, characteristic mental generals of this patient . Patient was prescribed with IGNIS ALCOHOLIS in 30 centesimal potency once a day for 1 month.


FOLLOW UP { Patient was followed up regularly every month

DATE symptoms medicine
  • Report date -27/8/2023
  • Ft3.-3.03 pg/ml
  • Ft4 1.08 ng/dl
  • TSH-5.160 μIU/mL
  • Hair fall more
  • Dizziness on and off
  • Headache has much reduced
  • No nausea
  • Constipation reduced
  • Physical generals
  • App- good
  • Thirst- increased
  • Stool- regular
  • Urine- no frequent urination
  • Perspiration- moderate
Rx IGNIS ALCOHOLIS 30 OD for 4 weeks
  • Hair fall is moderately reduced
  • Headache on and off in neck extending to occiput
  • Stool regular
Rx IGNIS ALCOHOLIS 30 OD for 4 weeks
  • Hair fall has reduced
  • Headache reduced
  • Generals good
Rx SAC LAC TDS for 4 weeks
  • Constipation on and off
  • Agg on spicy food
  • Her fear has reduced much
  • Dizziness was reduced
Rx IGNIS ALCOHOLIS 30 OD for 4 weeks
  • Report date – 26/12/2023
  • Ft3 3.23 pg /ml
  • Ft4-1.17 ng/dl
  • TSH- 3.46 μIU/mL
  • Weight- 62 kg
  • Hair fall reduced
  • Stool- no constipation
  • Appetite normal
  • Sleep well
  • Menses normal.
Rx SAC LAC 30 TDS for 4 weeks




1. Was there an improvement in the main symptom or condition for which the homoeopathic medicine was prescribed? +2 -1 0 Yes


2. Did the clinical improvement occur within a plausible timeframe relative to the drug intake +1 -1 0 Yes


3. Was there any initial aggravation of symptoms? 0 0 0 No


4 Did the effect encompass more than the main symptom or condition (i.e. were other symptoms ultimately improved or changed)? +1 0 0 Yes


5 Did overall wellbeing improve? (suggest using validated scale) +1 0 0 Yes


6 Direction of cure: did some symptoms improve in the opposite order

of the development of symptoms of the disease?

0 0 0  No


Direction of cure: did at least two of the following aspects apply to the order of improvement of symptoms-from organs of more importance to those of less importance—from deeper to more superficial aspects of the individual—from the top downward. +1 0 0 Yes


7 Did old symptoms (defined as nonseasonal and non-cyclical that were previously thought to have resolved) reappear temporarily during the course of improvements? 0 0 0 Yes


8 Are there alternate causes (other than the medicine) that—with a high probability—could have caused the improvement? (Consider the known course of the disease, other forms of treatment, and other clinically relevant interventions). -3 +1 0 No


9 Was the health improvement confirmed by any objective evidence? (e.g., lab test,

clinical observation, etc.)

+2 0 0 Yes


10 Did repeat dosing, if conducted, create similar clinical improvement? 0 0 0 Yes


Total score (Maximum score= +13; Minimum score = -3) Total


In this case, patient presented with complaint of hair fall, tiredness, constipation and weight gain and she was diagnosed as subclinical hypothyroid on correlation with laboratory investigation. Even though she has common symptoms of clinical condition, she had some peculiar mental generals and physical generals.

On   the basis of totality of characteristic symptoms ,case analysis was done and with help of Radar software, repertorization was done .In 6th edition of organon  aphorism, 154, Hahnemann states that, “ the most suitable medicine contain those peculiar, uncommon, singular and distinguishing (characteristic) symptoms, which are to be met with in the disease to be cured in the greatest number and in the greatest similarity, this medicine is the most appropriate Homoeopathic specific remedy for this morbid state”(13), which shows importance of characteristic , peculiar symptoms. Based on Hahnemannian principle,

An individualized Homoeopathic medicine IGNIS ALCOHOLIS(15) was selected as similimum for this patient.

IGNIS ALCOHOLIS(15) was  a medicine prepared by burning and combustion of  pure alcohol followed by potentization .Even though , it was not well proven remedy, it has peculiar dream and fear  symptoms noted from provers such as dreams of fire, silver fish, bats, rats, animals, lizards, buying and selling houses, etc.This striking general symptoms, matched with peculiar generals of the patient, irrespective of particular symptoms. So this remedy was selected and prescribed in 30 centesimal potency for the patient

TSH levels were investigated and analyzed before and after treatment. TSH before treatment, was 16.830   μIU/mL and TSH after 5 months of treatment is 3.46 μIU/mL.a marked improvement of symptoms also noted after the course of treatment.

Post treatment analysis was done using The Modified Naranjo Criteria for Homoeopathy  (MONARCH)10, for determining the causal attribution of clinical outcome after the Homoeopathic intervention. The total score was +9 thus suggesting the possible association between the medicine and the outcome. And this indicates positive role of individualized Homoeopathy medicine which was exact similimum for the patient. Patient had complete recovery of symptoms and restoration of her TSH levels to normal within 5 months. So, this case report was helpful in analyzing the effectiveness of individualized Homoeopathy medicine IGNIS ALCHOLIS in treating subclinical Hypothyroidism.

Hence this case report evidently suggests, effectiveness of individualized Homoeopathy medicine in treating subclinical hypothyroidism and also efficacy of rare remedy IGNIS ALCOHOLIS in this case.

This case also highlights the importance of individualization for selecting similimum and treating the patient and not disease


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Medical Director, Santham Homoeopathy Hospital And Research Centre, Chennai.

Assistant Medical Officer
Santham Homoeopathy Hospital And Research Centre, Chennai.

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